Modelo de red torsional

1. The TNM program computes the normal modes of the structure-based (elastic network) model of a protein of known structure in the space of torsion angles.
   For each residue, the degrees of freedom are the the phi and psi angles of the protein backbone (optionally chi and side-chains) and the rigid body degrees of freedom of protein chains or parts of the chain separated by disordered regions not seen in the protein structure.
   The TNM displace backbone atoms including C β maintaining their covalent geometry.

Publicaciones sobre el modelo de red torsional:

Más relevantes:

1. Dehouck Y, Bastolla U. The maximum penalty criterion for ridge regression: application to the calibration of the force constant in elastic network models. Integr Biol (Camb). 2017 Jul 17;9(7):627-641. [Pubmed]

2. Dos Santos HG, Klett J, Méndez R, Bastolla U. Characterizing conformation changes in proteins through the torsional elastic response. Biochim Biophys Acta. 2013 1834(5):836-46. [Pubmed]

3. R. Méndez and U.Bastolla. Torsional Network Model: Normal modes in torsion angle space better correlate with conformation changes in proteins. Phys. Rev. Lett. 2010 228103. [Pubmed]