The ElectroShape Polypharmacology server is a tool that enables any user to estimate polypharmacology profiles and side effects of compounds based on the molecular similarity concept.
ElectroShape1 is a method that compares the distance and charge distributions of a molecule from 4 different surrounding points, which allows its 3D similarity to other molecules to be assessed in a very fast and efficient way. In addition, the calculated molecular descriptors can be stored for further use, which speeds up subsequent searches.
In this server, you will find a web tool that uses the ElectroShape and1 SEA2 methods to estimate polypharmacology profiles for any compound using curated information available from DrugBank.