Miquel Coll
Institut de Biologia Molecular de Barcelona (CSIC)
Parc Científic de Barcelona
Josep Samitier 1-5
08028 Barcelona, Spain
Tel. (34) 93 - 403 - 4951
Fax. (34) 93 - 403 - 9976
mcoll@ibmb.csic.es
http://www.irbbarcelona.org/mcoll
http://www.ibmb.csic.es

Vitae

Miquel Coll is the head of the Structural and Computational Biology Programme at the Institute for Research in Biomedicine (IRB Barcelona) and the head of the Structural Biology Department of the Institute of Molecular Biology of Barcelona (IBMB-CSIC). He obtained his degree in Biology in 1982 and his PhD in 1986 from the University of Barcelona. In 1986 he joined the laboratory of Prof. Alexander Rich at the Massachusetts Institute of Technology and worked on the structural analysis of DNA. In 1989 he moved to the Max-Planck-Institut in Munich and worked, as a postdoc with Prof. Robert Huber, in the structural analysis of a number of proteins. In 1990 he started a protein crystallography research group at the CSIC. In 1999-2000 he spent a sabbatical year at the Grenoble Outstation of the EMBL. Miquel Coll is presently a CSIC Professor and has been Deputy Director of the IBMB-CSIC from 2002 to 2006. In 2000 he was elected member of the European Molecular Biology Organization (EMBO).

Scientific Interests

Our research focuses on the three-dimensional structure of proteins, nucleic acids and their complexes. We use a number of molecular biology and structural biology techniques, with a focus on X-ray diffraction crystallography. We examine systems related to horizontal gene transfer which involve the DNA translocation across the cell membranes. In addition, we address the regulatory mechanisms of gene expression and the control mechanisms of DNA replication. We also study unique DNA structures, like DNA junctions, and novel drugs that target DNA.

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