Manuel Rico
Instituto de Quimica Fisica "Rocasolano"
Serrano 119
Madrid 2006
Tel: (34) 91- 561 - 9400
Fax: (34) 91- 564 - 2431


Prof. Manuel Rico is a Senior Researcher of the Spanish Council of Scientific Research, adscribed to the  Department of Spectroscopy and Molecular Structure of the Institute of Physical Chemistry “Rocasolano” in Madrid (Spain). He is an expert in Nuclear Magnetic Resonance (NMR) Spectroscopy and in its application to protein folding, structure and dynamics .He has been awarded the National Research Award of the Spanish Royal Society of Chemistry (2002) and the National Award of Research in Chemical Science and Technology “Enrique Moles” of the Spanish Ministry of Science and Technology (2003).

Scientific interests

He and his group have made important contributions to the design of linear peptides with well defined conformations, either a-helices, b-hairpins or small three-strand antiparallel b-sheets. It is also significant his contributions in the protein folding field, in particular, his studies on folding kinetics, H/D exchange measurements, and denaturation equilibria, leading to the identification of residual structures in the random coil, and characterization of folding intermediates of several proteins, like l-cro 434, Rnase A, Che-Y, apo-flavodoxin, and some fragments and cyclic permutations of cytochrome b562. His is a reference lab for NMR structural determinations of proteins and nucleic acids all over Spain, and the number of his collaborations with other chemical or biochemical groups is certainly very large. At the international level, he is currently invited to lecture in meetings, courses and symposia on the applications of NMR in Structural Biology. He is author of more than 200 research works published in international journals, five book chapters, and has been the editor of three books on NMR spectrocopy.

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