Guillermo Montoya
Macromolecular Crystallography Group
Spanish National Cancer Center (CNIO)
Melchor Fdez. Almagro 3
28029 Madrid
Tel:: (34) 91 - 224 - 6900
Fax : (34) 91 - 224 - 6976


Guillermo Montoya obtained his Bachelor degree in Biochemistry at the University of the Basque Country in 1990 and his Ph.D in Chemistry at the University of Zaragoza in 1993. After he got his degree he obtained an EMBO and FEBS fellowships and moved to the Max Planck Institut für Biophysik in Frankfurt am Main. After this stay Montoya got a Marie Curie fellowship and spent eight years at EMBL-Heidelberg in Prof. I. Sinning group. In 1998 he was appointed as Researcher at the Spanish Research Council (CSIC) and he was awarded a Peter und Traudl Engelhorn Foundation Research Fellowship. Since 2003, Montoya is honorary professor of Biochemistry at the Autonomous University of Madrid and member of the working group in charge of the design of the biocrystallography beamline at the Spanish Synchrotron. Montoya has been head of the CNIO’s Macromolecular Crystallography Group since 2002.

Scintific interests

The human genome is a sophisticated and complex coding system able to produce thousands of different proteins in a tightly controlled way. Proteins rarely act alone; they typically interact with other macromolecules to perform particular cellular tasks. The resulting functional assemblies (complexes) are more than the sum of their parts.  These assemblies, the molecular machines of the cell, perform the majority of cellular functions. The structure determination of these complexes will help us to decipher not only the molecular mechanisms that rule them but also their protein-protein interactions. This research approach merges two complementary techniques, X-ray crystallography and electron microscopy, in order to combine the structural information at high and low-medium resolution.

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